
Ripped Fuel was a diet supplement sold at places like GNC and made by Twinlab. The original formula contained ephedra, a Chinese herb used in many diet supplements, which gave users energy and curbed their appetite. Two tablets of Ripped Fuel contained 20 milligrams of ephedra alkaloids. Ephedra is a stimulant similar to caffeine and amphetamines, increasing the user's heart and metabolic rates, and is linked to serious health risks like stroke and heart attack. Due to these health concerns, the FDA has received petitions to ban ephedra, and many supplement manufacturers have stopped using it in their products. Today, Twinlab Ripped Fuel is marketed as an ephedra-free fat burner.
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What You'll Learn

The original formula of Ripped Fuel contained ephedra
Each tablet of the original Ripped Fuel formula contained 10 milligrams of ephedra alkaloids, for a total of 20 milligrams in two tablets. This herbal supplement was not regulated as a drug and was classified as a food, meaning it did not require FDA approval before being marketed to the public.
The inclusion of ephedra in Ripped Fuel and similar products sparked controversy due to its potential health risks. Critics, including the FDA, linked ephedra consumption to serious side effects such as chest pain, stroke, seizures, and even death. The herb's chemical similarity to methamphetamine and its ability to convert into a form of amphetamine within the body raised further concerns.
In response to the growing concerns and incidents like the death of a 15-year-old girl, supplement manufacturers, including Twinlab, began to remove ephedra from their products. The original Ripped Fuel formula with ephedra is no longer available, and the company now offers an ephedra-free version of Ripped Fuel, marketed as a fat burner and dietary supplement. Despite the removal of ephedra, consumers are still advised to exercise caution and consult their physicians before using any dietary supplements.
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Ephedra is chemically similar to methamphetamine
Ripped Fuel was a diet supplement sold at places like GNC and made by Twinlab. The original formula contained ephedra, which, once ingested and metabolized by the human body, converts into a form of amphetamine. It gave users energy and curbed their appetite. However, it was also linked to serious health risks like stroke and heart attack.
The most popular method for reducing ephedrine to methamphetamine is similar to the Birch reduction, using anhydrous ammonia and lithium metal in the reaction. The second most popular method uses red phosphorus and iodine in the reaction with ephedrine. Ephedrine can also be synthesized into methcathinone via simple oxidation.
The European project Collaborative Harmonisation of Methods for Profiling of Amphetamine Type Stimulants (CHAMP) aims to harmonize profiling methods and create a common database to help identify relationships between drug seizures, drug sources, and trafficking routes. The identification of suitable habitats for Ephedra species is also essential for their protection and cultivation.
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Ephedra is linked to serious health risks
Ephedra, an ingredient in the original formula of Ripped Fuel, has been linked to serious health risks. Ephedra is a close chemical cousin of methamphetamine and has been used to bulk up cocaine. It is a natural stimulant that can speed up the nervous system and increase blood pressure and heart rate.
Ephedra has been linked to harmful side effects, even in low doses and with short-term use. These side effects include high blood pressure, heart attack, seizure, stroke, and psychosis. It can also cause anxiety, dizziness, dry mouth, headache, heartburn, insomnia, irritability, nausea, personality changes, and jitteriness.
The use of ephedra is considered especially unsafe for certain groups, including pregnant or breastfeeding people, children, and people with cardiovascular disease. It may also interact with other medications, such as antidepressants, diabetes medications, asthma medications, and liver medications, leading to serious health complications.
Due to these safety concerns, the FDA has banned dietary supplements containing ephedrine alkaloids, and ephedra has been banned from the Olympics, college athletics, and the National Football League. Despite these bans, ephedra is still found in some dietary supplements, particularly those marketed for weight loss and athletic performance.
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Ephedra is banned by the Olympics committee, the NFL, and the NCAA
Ephedra, also known as "Ma huang", was an ingredient in the original formula of Ripped Fuel, an herbal supplement sold as a diet pill. Each pill contained 10 milligrams of ephedra alkaloids, and the substance was also linked with serious health risks such as heart attacks, strokes, and seizures. In fact, the substance has been linked to around 80 deaths, including that of a 15-year-old girl.
Due to these health concerns, ephedra has been banned by several sports organizations, including the Olympics committee, the NFL, and the NCAA. The NFL's ban came after the death of Northwestern safety Rashidi Wheeler, who collapsed and died during a workout. Although Wheeler had asthma, toxicology tests revealed ephedrine in his system, sparking concern about the substance's role in his death.
The U.S. military has also recorded injuries and deaths among troops who consumed ephedra. Despite these concerns, ephedra remains popular, with an estimated three billion servings consumed annually. This popularity has been attributed, in part, to the classification of herbal supplements as food rather than drugs, which means they do not require FDA approval before entering the market.
The delay in banning ephedra has been attributed to pressure from the powerful ephedra industry, with critics arguing that the substance's dangers are well-established and warrant immediate action. In light of the health risks associated with ephedra, its addition to the banned substances list by the Olympics committee, the NFL, and the NCAA is a necessary precaution to protect the health and safety of athletes.
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Ephedra is no longer included in Ripped Fuel
Ephedra, also known as "Ma Huang", is a Chinese herb used in many dietary supplements as it contains stimulants similar to caffeine. It increases the user's heart and metabolic rates, burning more calories throughout the day. It was originally included in Ripped Fuel, a diet supplement sold at places like GNC and made by Twinlab.
However, ephedra has been linked to serious health risks, including chest pain, stroke, seizures, and even death. In 2002, CBS News reported on the growing criticism and concerns surrounding the safety of ephedra, with pharmacologists and consumer advocacy groups petitioning for a ban. The U.S. military had also recorded injuries and deaths among troops who had consumed ephedra.
The classification of herbal supplements as food rather than drugs meant they did not require FDA approval before entering the market. This classification also made it more challenging to force unsafe products off the market. Despite this, manufacturers of Ripped Fuel and other ephedra-containing products faced increasing pressure to remove the ingredient from their formulations.
As a result, Ripped Fuel no longer contains ephedra. The current formula for Ripped Fuel by Twinlab is ephedra-free and marketed as a clinically proven weight loss and fat-burning supplement. It contains a combination of ingredients, including green tea leaf extract, caffeine, and cocoa, which are intended to promote weight loss and target stubborn fat storage areas.
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Frequently asked questions
Two tablets of Ripped Fuel contained 20 milligrams of ephedra alkaloids.
Ripped Fuel was a diet supplement sold at places like GNC and made by Twinlab. The original formula contained ephedra, which gave users energy and curbed their appetite.
No, ephedra is not safe. It is a stimulant similar to caffeine and amphetamines and has been linked to serious health risks like stroke, heart attack, and seizures. The FDA has been warning consumers of these possible side effects for almost 10 years, and many supplement manufacturers have stopped using ephedra in their products.











































